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The high-end maintenance dose of 2.4 mg per week is commonly used in protocols like Wegovy for sustained weight management
Moreover, reduced expression of uterine receptivity markers, for example, integrin, HOXA10 and IGFB1, and increased expression of inflammatory factors, such as TNF and NF-B, contribute to increased cell proliferation in PCOS 134,136,137
While older medications only pulled the GLP-1 lever, tirzepatides unique ability to activate both GIP and GLP-1 pathways leads to more significant results in both weight loss and blood sugar regulation
There is definitely awareness of Ozempic, and increasingly of Wegovy, and we can build on that, says Dave Moore