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Similarly, hydration also matters: collagen requires water to function, and dehydrated skin shows texture changes more prominently

This has not been confirmed in humans, and UK SmPCs for licensed GLP-1 receptor agonists classify this as a precaution rather than a contraindication

& Boster, J

This next-gen GLP-1 appetite suppressant blends ancient wisdom with modern science in a concentrated drop form, supporting appetite regulation, fat metabolism, and blood sugar stability without synthetic shortcuts

Tirzepatide (Zepbound, Mounjaro) A 2022 clinical trial of people with obesity or overweight found that a once-weekly tirzepatide injection produced an average weight loss of 15%21% in 72 weeks (a bit less than a year and a half)