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[44] The incidence of side effects specific to a medication can be affected by the type of access (peripheral versus central), the rate of administration, or the quantity of drug administered

Direct oral NAD supplements exist, but many people choose NMN or NR because they are designed to support NAD+ production through precursor pathways

For drugmakers, the advantage may lie not only in clinical outcomes, but in whether patients can stay on therapy and what happens when they try to stop.