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A recent study found that the ferroptosis inducer erastin can induce cellular autophagy, and autophagy can trigger ferroptosis by degrading ferritin and transferrin receptor 1 (TfR1), resulting in the accumulation of intracellular iron

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TCA cycle defects and cancer: When metabolism tunes redox state

doi: 10.1016/j.neuron.2014.01.037, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 78

As per 2009 data from the United States Renal Data System (USRDS), annual reported incidence and prevalence of advanced chronic kidney disease (CKD) were 354 and 1665 per million people, respectively