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Candidate polymorphisms in this context include cSHMT -C1420T, a common gene variant in cSHMT which results in an amino acid substitution that prevents the multienzyme complex from undergoing localization to the nucleus

require documentation of indication, dosing, and clinical response Biologics (IL-12/23 inhibitor): Ustekinumab (Stelara, J3357) FDA-approved for moderate-to-severe CD

Having an intestinal disorder resulting in less stomach acid : Research suggests that these include conditions like gastritis, hypochlorhydria or achlorhydria

(PubMed) Gross CJ, Henderson LM, Savaiano DA

These ingredients can irritate the gut, especially in individuals with sensitive digestive systems, potentially resulting in diarrhea