Finally, the PLB dosage and administration strategy should be refined, and its long-term effects and potential side effects should be comprehensively evaluated to confirm its safety and effectiveness in clinical applications
The 50mg intranasal spray formulation provides additional scientific value by allowing laboratories to investigate formulation stability, spray consistency, peptide integrity, copper complex stability, physicochemical characteristics, analytical reproducibility, and intranasal delivery system performance
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George AK, Majumder A, Ice H, Homme RP, Eyob W, Tyagi SC, Singh M (2020) Genes and genetics in hyperhomocysteinemia and the 1-carbon metabolism: implications for retinal structure and eye functions
Incorporating studies with negative or null results will help mitigate publication bias and contribute to a more accurate, evidence-based understanding of the role of natural products in AD