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NNMT upregulation also elevates homocysteine levels, activating pro-inflammatory and pro-oxidative cascades (TLR4-NF-B and STAT3-IL-1 pathways) linked to atherosclerosis, heart failure, and coronary heart disease

Medical Journal of Australia , 199: S27-S32

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Its the dual-action choice for properties in known deficient areas, particularly around lambing and calving when nutritional demands are at their peak