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640 Eicosapentaenoic acid and docosahexaenoic acid can also effectively relieve pentylenetetrazol-induced seizures and depression by reducing iron levels in the brain, promoting M2 polarization of microglia, and activating Nrf2

This disruption leads to neurological and hematological damage similar to that seen in N 2 O abuse, including posterior column lesions in the cervical and thoracic spinal cord, demyelination, or axonal injury of peripheral nerves

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