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Description

Caffeine can make you produce more urine and, as a result, cause you to experience dehydration if youre not drinking enough water

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1 mg to 2 mg) First-line OTC: Bismuth subsalicylate 262-524 mg before meals Second-line OTC: Simethicone 125-250 mg after meals

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Bay Staters use of weight-loss medications, such as Ozempic and Wegovy, has surged in recent years, and health policy officials are concerned about the impact of the soaring drug prices on overall pharmaceutical spending

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FDA-approved pharmacotherapy alternatives include several options with established safety profiles: Semaglutide (Wegovy): A GLP-1 receptor agonist producing 12-15% weight loss, with cardiovascular benefits demonstrated in the SELECT trial and FDA-approved indication for reducing cardiovascular risk Liraglutide (Saxenda): A GLP-1 receptor agonist producing 5-8% weight loss [4] Phentermine-topiramate (Qsymia): FDA-approved combination producing 7-10% weight loss with established safety data Naltrexone-bupropion (Contrave): Combination targeting reward pathways and appetite, producing 5-9% weight loss [4] Orlistat (Xenical, Alli): Lipase inhibitor producing 3-5% weight loss with gastrointestinal side effects [4] Setmelanotide (Imcivree): For rare genetic obesity disorders (POMC, PCSK1, LEPR deficiency) [4] Metabolic and bariatric surgery should be considered for patients with BMI 40 kg/m or 35 kg/m with obesity-related comorbidities who have not achieved adequate weight loss with nonsurgical interventions

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