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Plus, since just 5% to 7% of body weight loss can help prevent prediabetes too, GLP-1 medications are helpful across the whole spectrumfrom diabetes prevention to management

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Do not discontinue your medication without consulting your prescriber, as abrupt cessation may affect your diabetes control or weight management progress

Further analyses revealed that cotadutide 300 g improved lipid profiles, liver enzyme levels (AST and ALT), and markers of liver fibrosis, including propeptide of type III collagen, and fibrosis-4 index, compared to placebo

Had we assessed risk of bias for less objective outcomes, such as participant-reported gastrointestinal adverse events, overall risk of bias for such outcomes in these trials might have been deemed of some concern