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3.9 In Vivo characterization 3.9.1 Behavioural parameter Behavioural parameters like rotarod, actophotometer, and balance beam are assessed in Parkinsons disease to evaluate motor coordination, activity levels, and balance, which are commonly impaired in the condition and the scores of each parameter is depicted in Figure 5 (Hong et al., 2020)

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By temporarily blocking this signal, BoNT-A produces a controlled reduction in muscle activity, softening the appearance of dynamic facial lines