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doi: 10.1038/s41591-022-02026-4 Jastreboff AM, Aronne LJ, Ahmad NN, et al

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In contrast, angiogenic factors promote changes in extracellular factors and contribute to immunosuppressive TME formation, such as peripheral dendritic cell (DC) maturation, inhibition of T-cell activation, and polarization of macrophages toward the M2-like tumor-associated phenotype 55