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The absence of standardized criteria for ovarian dysfunction and poor responder classification limits generalizability across studies, complicating the identification of target populations ( 5.2 Recommendations 5.2.1 Pathway-centric trials Mitochondrial and Redox Pathways: Targeted interventions aimed at enhancing mitochondrial function and redox balance are critical for improving oocyte quality

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But others report no noticeable changes even after months of consistent use, and some experienced side effects

[DOI] [PubMed] [Google Scholar] 199.Chatterjee A., Gupta S

In 2025, a recent study of Hu et al