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Some effects will be felt immediately but many such as body composition changes, take 3-6 months of treatment

doi: 10.1007/s12325-017-0595-7 Summary Keywords dipeptidyl peptidase-IV inhibitor, efficacy, glucagon-like peptide-1, linagliptin, prediabetes, type 2 diabetes Citation Chong SC, Sukor N, Robert SA, Ng KF and Kamaruddin NA (2022) Endogenous GLP-1 levels play an important role in determining the efficacy of DPP-IV Inhibitors in both prediabetes and type 2 diabetes

However, by boosting natural growth hormone production, it can help improve energy, body composition, and recovery in ways that complement healthy testosterone levels

Low doses of tamoxifen act as agonists in IGF-1-stimulated breast cancer cells and further increase IGF-1 expression