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En cultivos de adipocitos, la inhibicin de NNMT con este compuesto se ha asociado con incremento de NAD+ intracelular, activacin de AMPK y aumento de la beta-oxidacin de lpidos, reduciendo el tamao de las gotas lipdicas en modelos celulares

These improvements position the compound as valuable for investigating the NAD+ metabolic basis of insulin resistance and diabetes pathophysiology