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Clinical evidence, encompassing trials, epidemiological investigations, and findings from animal toxicology and histological studies, has revealed potential associations between GLP-1RAs and the risk of neuroendocrine tumors and exocrine pancreatic dysplasia, with some evidence suggesting an increased risk of pancreatic cancer [6]

10.1016/j.numecd.2006.04.003 280 WalidA.-D.MolhamA.-H.AhmedA.-G

In the Phase 2 NEJM trial (2023), participants on 12 mg lost an average of 24.2% of body weight at 48 weeks

Recent Developments: In Mar 2025, CordenPharma launched a greenfield peptide manufacturing plant in Basel, Switzerland, into operation