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Genetic control of biosynthesis and transport of riboflavin and flavin nucleotides and construction of robust biotechnological producers

Antioxid Redox Signal , 2003

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5,714,576, issued February 3, 1998, to V

Normal aging is accompanied by a decline in cerebral metabolism, driven by impaired mitochondrial ATP production, increased reactive oxygen species (ROS), and decreased antioxidant defenses (Maldonado et al., 2023), and these deficits are amplified in ADRD compared to cognitively normal older adults (Patro et al., 2021