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Situation-specific supplements Vitamin B12: Particularly important if you take metformin alongside semaglutide, as metformin can deplete B12 levels

Instead, use an FDA-cleared sharps disposal container or a sturdy household container with a tight-fitting lid, like a heavy-duty plastic container

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These medications may not be suitable for everyone and do have medication interactions, so be sure to discuss your entire medical history with your healthcare provider to see whether trying a PDE5 inhibitor would be safe for you