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Across repeated weekly doses the drug accumulates to a steady state, so trough levels hold high enough to maintain therapeutic effect, without a cliff-like drop before the next dose

Thats why it is so important to work with a provider. Can GLP-1 Medications Work Without Medical Guidance

Onuma H, Inukai K, Kitahara A, Moriya R, Nishida S, Tanaka T, et al

"For now I am back to exercise and willpower, but I look at my colleagues leaner but not hungrier and I hope that if science can do it for them, maybe one day it can help me, and everyone else." Charles Barkley said he lost 62 pounds on Mounjaro

The sustained effects of a dual GIP/GLP-1 receptor agonist, NNC0090-2746, in patients with type 2 diabetes