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This may indicate that ligand binding interactions here are primarily mediated through side chain interactions, or that any stabilization to amide hydrogen is below the limit of detection with this approach

We also tested the sodA and spxB mutants that have previously shown a lower phenotype than wt [6, 32], although these strains displayed a higher H 2 O 2 resistance than the mentioned mutants, but significantly lower compared with the wt strain (Fig 3B, Fig S2)

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