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doi: 10.1016/j.jaci.2021.03.033 30 EvertsBAmielEvan der WindtGJFreitasTCChottRYarasheskiKEet al

As a result of intensive blood glucose control through pharmacological intervention, it is possible to delay CKD progression with standard therapies for treatment of T2DM

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The authors suggest that besides correlated to poor survival, high B7-H3 expression may be correlated to refractoriness to anti-PD-1/programmed death-ligand 1 (PD-L1) immunotherapy by impairing CD8+ T-cell mediated tumor immunity

As youll see below, each GLP-1 approach has its own set of benefits and drawbacks