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Suomalainen A, Battersby BJ

Heruye SH, et al

Persistent synovitis can induce VEGF production, promoting neovascularization and increased vascular permeability (143), which may facilitate the influx of iron into the joint cavity and subchondral bone and recruit additional immune cells, thereby intensifying local oxidative stress and inflammatory cascades (144)

El GHK-Cu no acta sobre una sola diana: entra en la clula por el receptor LRP1 y modula la expresin de miles de genes humanos, adems de entregar cobre directamente a la mitocondria

These findings indicated an extensive affinity between DEHP and disease targets, providing evidence for DEHP-induced BRCA from the molecular docking perspective