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During tumor removal, the periosteum of the mandible was preserved to minimize deficits in mandibular development, and teeth were identified in the tumor that was removed

Moreover, excess iron could promote the formation of reactive oxygen species (ROS), which can lead to oxidative stress and DNA damage, with cytokine-regulated inflammatory pathways and a central contribution from innate immune cells in the tumor microenvironment (360, 361)

Premature increases often worsen side effects without improving results