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Offering both once-weekly and once-daily dosing options, tirzepatide exhibits substantial reductions in HbA1c levels, often outperforming other GLP-1 receptor agonists

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On the other hand, certain studies have demonstrated the overexpression of GLP-1R in brain tumors, embryonic tumors, gut and lung neuroendocrine tumors, including other endocrine tumors like Pheochromocytomas, raising concerns that existing GLP-1RAs can contribute to tumor growth in humans (Shilyansky et al., 2025