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Non parametric statistic analysis was performed for categorical data using Kruskal-Wallis and post hoc Mann-Whitney U test

The BDNF fragment (aa 104-115) is critical for BDNF-TLR4 interaction, and the corresponding synthetic BDNF-derived dodecapeptide (BDP-12) retains TLR4-antagonistic and anti-inflammatory effects both in vitro and in vivo, without pro-proliferative side effects

in the 100 mg dose present here, serious GI effects are uncommon, but mild nausea or stomach discomfort could occur in sensitive patients

LC-MS/MS can distinguish GSH and GSSG through analyte-specific transitions and quantify them simultaneously or in parallel

These toxic metals disrupt thyroid function, deplete essential minerals (like zinc and selenium), damage follicle cells directly, and create oxidative stress that accelerates hair thinning