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One notable immunogenicity finding from that same trial is worth highlighting for researchers: antibodies developed in almost 50% of patients receiving tesamorelin, although the study authors noted this was a relatively short-duration trial and did not report this antibody development as being associated with a loss of efficacy or a distinct safety signal within the study period
For mood, a meta-analysis of 26 randomized controlled trials found EPA-dominant omega-3 formulations to be superior to DHA-dominant or balanced formulations for reducing depressive symptoms, with effect sizes comparable to some antidepressant therapies [18]
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