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Analyses of centella material put Asiatic Acid reported in the range of 0.2-3% of the extract

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In October 2023, the Journal of the American Medical Association examined adverse events associated with GLP-1 receptor agonists prescribed for weight loss, and researchers concluded that using the drugs increases the risk of gastrointestinal adverse effects, such as biliary disease, pancreatitis, bowel obstruction, and stomach paralysis