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Retrospective EHR-based studies can capture real-world associations, yet they are especially vulnerable to residual confounding, treatment-selection bias, differences in healthcare engagement, and unmeasured disease biology

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Additionally, GLP-1 promotes the growth and proliferation of pancreatic cells, inhibits glucagon secretion, and enhances peripheral tissue uptake of glucose, making it a key factor in maintaining stable blood glucose levels

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5h), suggesting that ferroptosis is not involved in the cold-induced death observed in the slcr-46.1 mutant