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Insulin secretory granule biogenesis and the proinsulin-processing endopeptidases

Compound 1 was isolated by silica gel column chromatography using a dichloromethane/methanol (DCM:MeOH = 60:1, V/V) eluent (yield: 80%)

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Based on these result, it can be concluded that manipulation of LPO derived products could present a new avenue for cancer treatment especially those fuelled by Wnt/-catenin oncogenic pathway

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