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Furthermore, the maximum rate of exchange occurs when the pH is high, and its value exponentially increases with the increase in the pKa of the imidazole ring itself ( Another interesting class of carbon atoms that may serve as deuterium traps are the bis-allylic carbon atoms, notably present in both microbial breakdown products of haem and in polyunsaturated fatty acids (PUFAs)

Links Competing interests The authors declare no competing interests

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If your DIY product shows any of these signs, discard it and make a fresh batch

Enjoy the nourishing benefits of this cream for soft and supple skin