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February 2026

Moreover, chronic treatment with liraglutide showed an increase in stem cell proliferation and differentiation into mature neurons in APP/PS1 mice and controls at all ages, which may have beneficial effects in neurodegenerative disorders like AD (168)

This is thanks to its active ingredient, orforglipron , which is a non-peptide

While peptide-based GLP-1 receptor agonists such as Exenatide, Liraglutide, Dulaglutide, and Semaglutide have demonstrated strong efficacy, there remains significant interest in developing next-generation therapies

Review your complete medication list with your healthcare provider to identify any other drugs that may contribute to xerostomia, as dose adjustments or alternative medications may be possible in some cases