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half-maximal effective concentration (EC 50 ) values (mean s.d.) of iFSP1 ( 1 ) and its derivatives ( 2 14 ) calculated from experiments performed at least twice in triplicate are shown in the table with the corresponding chemical structures depicted below

Researchers at the University of Texas Medical Branch first characterized 5-amino-1mq in 2017 while searching for ways to inhibit NNMT, an enzyme they had identified as a key regulator of fat cell metabolism

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