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Third, we synthesize key preclinical studies and randomized controlled trials published in the last 10 years to provide a timely and critical appraisal of efficacy and safety

0.11%] and met the pre specified non inferiority margin (0.4%)

Appropriate candidates typically include patients who have achieved postoperative stability, demonstrate inadequate weight loss (less than 50% excess weight loss) or significant weight regain (typically defined as regaining 25% or more of lost weight), and have persistent obesity-related comorbidities despite surgical intervention

[47] In Kurzzeitstudien hatte Carnitin sowohl oral verabreicht als auch injiziert eine anti-ischmische Wirkung