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10.1101/2024.11.19.624390 bioRxiv

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In addition, they refrigerate it once mixed

However, whether or not albuminuria is a clinically relevant renal outcome remains unclear

This is why the recommendation for T/T individuals is specifically active folate rather than folic acid folic acid accumulates as unmetabolized folic acid in the circulation of T/T individuals, potentially with pro-inflammatory consequences, rather than supplementing the genuinely deficient 5-MTHF pool