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Subsequent gene-expression analyses cited in the review identified GHK-Cu as modulating expression of approximately one-third of human genes, with a pattern consistent with reversal of age-related transcriptomic shifts

4.3 Diabetic cardiomyopathy Extensive evidence supports the broad-spectrum cardioprotective properties of GLPs, which effectively counteract diverse cardiac pathologiessuch as pathological myocardial hypertrophy, viral or autoimmune myocarditis, atherosclerotic plaque development, sepsis-associated myocardial depression, ischemia-reperfusion injury, and cardiotoxicity triggered by chemotherapeutic agents (Ubaidillah et al., 2016

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Conclusion Metformin and GLP-1 medications each support weight loss through unique pathwaysbut when used together, they may deliver enhanced and sustainable results

Inulin (10,000 mg/day), L-carnitine (1,000 mg/day) and LC n3-PUFA (6,000 mg/day) reduced, respectively, by 0.06, 0.19 and 0.42