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This slowed digestion means that food spends more time in the digestive tract, which can result in increased fermentation by gut bacteria, leading to the production of gas

TRIUMPH-4 (December 2025) TRIUMPH-1 (May 21, 2026) The consistency between TRIUMPH-4 (28.7%) and TRIUMPH-1 (28.3%) in different populations, different durations is exactly what the FDA looks for in a robust efficacy package

More specifically, GLP-1 agonists can slow the absorption of oral drugs, potentially altering their effectiveness and timing

Mohapatra B, Ahmad G, Nadeau S, Zutshi N, An W, Scheffe S, Dong L, Feng D, Goetz B, Arya P, et al