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A Bayesian hierarchical model was fitted using the brms framework, specifying percent weight change as a Gaussian outcome with (i) drug-specific smooth dose effects (splines by drug), (ii) treatment duration included as a covariate to account for variability in follow-up time across trials, and (iii) a study-level random intercept to account for between-trial heterogeneity

2-adrenergic agonists such as terbutaline, or related pharmacological interventions, can modulate Arg metabolism-related processes and shift the polarization balance by affecting pathways such as high-mobility group box 1 (HMGB1) and nuclear factor-B (NF-B)

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Weight Loss: Many individuals with type 2 diabetes struggle with weight management