Whilst the NHS notes that taking up to 2,000 micrograms daily is unlikely to cause harm in most people, there is generally no benefit to consuming such excessive amounts unless treating confirmed deficiency under medical supervision
Additionally, the pain will often be associated with other symptoms, such as: Paresthesia: an abnormal sensation, whether spontaneous or evoked, typically not painful, according to the International Association for the Study of Pain
Researchers studying the broader axis often combine IGF-1 LR3 work with separate studies using GH secretagogues like CJC-1295/Ipamorelin or Tesamorelin to drive endogenous GH and IGF-1 production, then compare results
They also studied solutions containing 5 g of B12 with vitamin C and found that 300 mg of vitamin C reduced the B12 content by about 40%
If youre struggling with low levels, b12 injection vitamin treatments could be the solution you need