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It targets the histidine sensor kinase QseC, a receptor in a broad spectrum of pathogens, inhibiting downstream QseC-mediated production of virulence factors

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One study, though, showed that even though TNF-alpha and IL-8 (inflammatory cytokines) levels were statistically in the same range as the healthy control group, the pain intensity was higher in fibromyalgia patients in accordance with higher TNF and IL-8 levels