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This well-structured study design underscores the importance of rigorous clinical trials in evaluating the efficacy and safety of new therapies

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According to the literature, says Christina OConnor, RD, with Pendulum Therapeutics, [berberine] should be taken approximately 30 minutes before meals to minimize blood sugar spikes and prevent any gastrointestinal side effects. She adds that the maximum dose is 900-1500 milligrams per day, with the doses split up three to four times throughout the day

It signals the brain to regulate appetite, promotes feelings of fullness making it essential for managing weight and overall metabolic health.* HOW TO TAKE: Take 4 capsules a day, preferably 15-30 minutes before meals

Mao et al., 2019a)