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The dose that reaches fibroblasts is still low compared to what systemic delivery achieves

We still face several challenges: We need large-scale, randomized controlled trials specifically in RA, psoriasis, and PsA populations We need to understand the long-term effects of these drugs in autoimmune conditions We need to determine the optimal dosing and treatment duration for these new indications What This Means for You: A Personal Note As your rheumatologist, my primary concern is your well-being

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