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Despite its potential, the integration of nanomedicine into clinical practice faces challenges, including the need for rigorous safety evaluations, immune reactions, regulatory approval, long-term stability, and the development of scalable manufacturing processes alongside ethical frameworks

ACSS2 KO cells had no impairment of 2D cell growth but showed a modest defect in the numbers and size of soft agar colonies formed compared to parental controls (Figure 1B, C

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Inhibition of tumor invasion and angiogenesis Malignant and aggressive forms of cancer can invade surrounding tissues and spread to distant tissues once cancer cells have acquired the ability to leave the primary site (reduced cell-to-cell adhesion and loss of polarity), migrate, and disseminate

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