can semaglutide make you thirsty Does Pee a Lot? Urinary Side Effects Explained How to Make Semaglutide More

This is true whether the caloric deficit comes from eating less, exercising more, or using any weight loss medication including appetite-suppressing peptides

GLP-1-Induced AMPK Activation Inhibits PARP-1 and Promotes LXR-Mediated ABCA1 Expression to Protect Pancreatic beta-Cells Against Cholesterol-Induced Toxicity Through Cholesterol Efflux

Yang, K., Wang, X., Song, C., He, Z., Wang, R., Xu, Y., Jiang, G., Wan, Y., Mei, J., & Mao, W

La semaglutida estimula la secrecin de insulina en las clulas beta pancreticas de manera dependiente de glucosa y suprime la liberacin de glucagn en las clulas alfa

I would not recommend it as a first-line approach