did not observe significant differences in amputation risk between GLP-1 receptor agonists, SGLT-2 inhibitors, and other diabetes medications in a large retrospective cohort study of 1,222,436 patients with type 2 diabetes
Special considerations and populations Certain groups should exercise extra caution with any GLP-1 product, whether prescription or supplement
Hengrui, Kailera's GLP-1 pill posts encouraging efficacy but high side effect rates in late-stage China trials The GLP-1 pill being developed by Hengrui Pharma and Kailera Therapeutics posted decent results in two late-stage China-based trials one in obesity and the other Sign up to read this article for free
GLP-1 medications can help manage type 2 diabetes and obesity, but they may cause short-term mild-to-moderate side effects such as nausea, vomiting, diarrhoea, constipation, bloating, and decreased appetite, particularly at the beginning of treatment
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