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Statistical evaluation was conducted by one-way ANOVA followed by a Tukeys post hoc test

Human studies have shown that PYY delays gastric emptying and promotes satiety (165), while short-term intravenous administration of PYY3-36 , at doses generating physiologic postprandial blood excursions, was shown to decrease calorie intake by approximately 30% in lean and obese subjects, without causing nausea, affecting food palatability, or altering fluid intake, nor was it followed by compensatory hyperphagia (166)

Additionally, the functionalization of POx with targeting ligands like antibodies or peptides makes these systems more effective in reaching the diseased tissues, thus moving closer to the goal of personalized medicine [25,26,27]

Suitable for laboratory & in-vitro research