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JAMA Otolaryngology, 136, 1367-1372

52.8 years)

In some instances, a hyaluronidase is a human hyaluronidase (e.g., hyaluronidase found in human sperm, PH20 (Halozyme), Hyelenex (Baxter International, Inc.))

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Alpha arbutin, on the other hand, does not trigger this rebound response because it regulates pigment production rather than shutting it down completely