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You can be so, you know, wired on caffeine that you're actually danger to yourself and others on the road, but you have no idea 'cause you've been awake for a day and a half, that sort of thing

This effectively reduces the overall baseline protection for new medicines from 10 to nine years, with implications for product launch strategies

J Clin Endocrinol Metab 103(6):23292335

[DOI] [PMC free article] [PubMed] [Google Scholar] Doyle KM, Bird DA, alSalihi S, Hallaq Y, CluetteBrown JE, Goss KA, Laposata M (1994) Fatty acid ethyl esters are present in human serum after ethanol ingestion