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Glucagon-like peptide-1 receptor agonists induce glucose-dependent insulin secretion, beta-cell protection, and other extraglycemic benefits such as weight loss and improvement in markers of cardiovascular risk
10.1097/00001756-199906030-00004 95 OlshanskyS
Understanding how these medications work is essential context for evaluating their potential effects on bone health, as both their metabolic actions and the weight loss they induce may theoretically influence bone density and skeletal integrity
Even at microdoses, these effects can contribute to better heart health, especially for individuals with risk factors like high cholesterol or hypertension
Endothelial GLP-1 (glucagon-like peptide-1) receptor mediates cardiovascular protection by liraglutide in mice with experimental arterial hypertension
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