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Of pathophysiological importance, circulating cholesterol is a major component of atherosclerotic plaques [64]

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Recent studies have begun to explore these metabolic pathways as potential therapeutic targets

Physiological melanin hyperpigmentation is the result of increased melanin biosynthesis by melanocytes in the basal cell layer of the oral epithelium, but pathological melanin pigmentation may be the result of increased number of normal melanocytes or atypical melanocytes, of increased melanogenic activity of normal or atypical melanocytes, or of both

Peptides are short chains of amino acidstypically 250 residuessmall enough to act like highly targeted biological messages but large enough to be very specific for a receptor or enzyme