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Patients should rotate injection sites (abdomen, thigh, or upper arm), allow the medication to reach room temperature before injection, and ensure proper technique

This is a genuine gap in the literature, and clinicians typically default to injectable routes when the target tissue is outside the gastrointestinal tract

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Forty-five residues (H433-F477) were truncated at the C terminus to improve the thermostability and an affinity tag, HPC4 tag, was added to the C terminus (GP64-HA-GCGR-GSGS linker-HPC4)